For people recovering from long-term opiate addiction, maintaining abstinence on a continual basis can be especially difficult. Long-term addictions tend to leave the brain in a weakened state in terms of its ability to regulate the body’s functions as normal. Under these conditions, medication therapies such as Suboxone treatment become necessary.
Suboxone, one of two brand names for buprenorphine, is specifically designed to treat the types of residual withdrawal effects that make ongoing abstinence so difficult to come by. Suboxone works by blocking opiates from triggering chemical reactions in the brain.
The length of time Suboxone can block opiates depends on different factors that influence the rate at which the body metabolizes the drug. Understanding how Suboxone treatment works can give you a better idea of how long Suboxone’s blocking effects will last.
Feel free to call our toll-free helpline at 877-743-0081 (Who Answers?) to ask about available Suboxone treatment options.
How Does Suboxone Block Opiates?
Suboxone is a synthetic opiate drug that contains two ingredients: buprenorphine and naloxone. Buprenorphine, a synthetic opiate agent, occupies the same brain cell receptor sites as addictive opiate drugs and thereby prevents addictive opiates from forcing these cells to release excess amounts of neurotransmitter chemicals. According to the Journal of Psychiatry, buprenorphine’s effects work to support normal chemical secretion rates, which helps to restore a normal chemical balance in the brain.

Suboxone can usually block opiates for 1 to 3 days.
Naloxone, the second ingredient in Suboxone, also occupies affected cell sites, but does so for the purpose of discouraging a person from relapsing back into old drug-using behaviors. In effect, someone who abuses opiates while on Suboxone will experience severe withdrawal symptoms due to naloxone’s blocking effects.
Suboxone Half-Life Effects
A drug’s half-life duration marks the amount of time it takes for the body to metabolize and eliminate half of what was ingested in terms of dosage amount. In effect, a drug’s half-life helps determine how long its intended effects will last.
According to the Food & Drug Administration, Suboxone’s buprenorphine ingredient has a half-life duration of 37 hours, whereas the naloxone portion has a half-life of 1.1 hours. This means, 37 hours after taking Suboxone, half of the buprenorphine portion will have left the body’s system. With naloxone, it takes just over an hour for half of what was ingested to leave the system.
Duration Effects
The length of time Suboxone blocks opiates varies depending on a range of factors, including:
- Length of time on Suboxone
- Body weight
- How often a person takes Suboxone
- Potential drug interactions
Each of the above factors has an effect on the body’s metabolism rate, which ultimately determines how long Suboxone’s effects last. In cases of long-term Suboxone treatment, the drug has time to build up in the body’s tissues, which tends to prolong Suboxone’s ability to block opiates with each successive dose. Likewise, frequency of Suboxone use can also have the same effect.
People who take other types of medications or abuse drugs while in Suboxone treatment may experience prolonged or shorter duration effects depending on whether the other drug slows or speeds up the body’s metabolism rates.
On average, Suboxone can block opiate effects anywhere from one to three days depending on the types of factors at work.
If you or someone you know are considering Suboxone treatment and need help finding a Suboxone program, call our toll-free helpline at 877-743-0081 (Who Answers?) to speak with one of our addiction specialists.
What is Subutex and Is it a Safe Treatment for Opiate Addiction?
5 Ways to Know Buprenorphine Treatment is Right for You -
Buprenorphine can be an incredibly helpful medication for many individuals. Depending on your needs, you may want to choose buprenorphine as the opioid treatment medication for your recovery. Call now to find rehab centers that provide options to help patients to create a well-rounded treatment program. 1. You Have a Mild Dependency on Opioids If ...
Will Opium Addiction Treatment Cure My Drug Problem? -
Opium and opium-based drugs breed some of the worst forms of addiction compared to other types of drugs. Addiction in any form happens over time as the brain incorporates a drug’s effects within its chemical workings. Once the brain becomes dependent on opium, it’s working at a diminished capacity due to the damaging effects of ...
Do I Need Residential Care for Fentanyl Addiction? -
Fentanyl is an extremely intense medication that is only normally given to those individuals who absolutely require it. Therefore, if you have been struggling with fentanyl addiction, you will likely need to attend residential care in order to recover safely. Call to find rehab centers that will cater to your needs and help you end ...
The Dangers of Abusing Heroin & Prescription Pain Pills and the Need for Opiate Addiction Treatment -
Both heroin and prescription pain pills belong to the same class of drugs known as opiates. While heroin’s designation as a Schedule I class controlled substance makes for one of the most addictive substances around, prescription pain pills fall under the Schedule II class designation, which can be just as addictive depending on the drug ...
10 Signs You Need Addiction Treatment for Opium -
If you're experiencing any of the following symptoms or warning signs, you should seek opium addiction treatment immediately.